Slip ups like this always happen at the grand slam events with top players losing unexpectedly. To be honest anyone could stop Andy.
Got to feel sorry for Djokovic though, he's had a tough year.
Nadal is playing really well but he's in the other half of the draw and seeded to meet Federer in the quarters. They will both be weighing up their chances also Nishikori, Raonic and Wawrinka. Lots of work to be done but I'm keeping my fingers crossed for Andy.
Surely Nadal's set to meet Raonic in the quarters (and that's only assuming he "upsets" Monfils, who is seeded higher)? It's Murray who may have to take Federer on at that stage, although Federer has to face first Berdych and then Nishikori (probably).
Murray's path to the quarters has opened up a little. No need to worry about Isner or Pouille, while Querrey is dangerous but perhaps less so on a hard court.