jumbo 1,00

[hope3fully]

33d not out to stop a nation producing radioactive material 8 a- - - t- -n- 42d visibly nervous fool cheating( not to worry) 9 a-i c ing 31 nothing more to italian----- male is in a sense duller 5

[Lie-in King]

33d Astatine - 'in' (not out [in]) 'a state'
42d Twitching - 'twit' + 'ch(eat)ing' (eat = worry)
31d Opium - 'O' (nothing) + 'piu' (It. "more") + m(ale)

[hope3fully]

many thanks Lie-in-King