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beta-blockers & Stjohns wart

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heft101 | 17:02 Sun 28th Apr 2002 | Body & Soul
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is it safe to take st John`s wart and beta blockers together
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Not without talking to your doctor. St Johns Wort inhibits p450, a metabolic enzyme that breaks down drugs. Thhis can have a severe effect on drugs like beta blockers. Also it is active in the catecholamine cycle, which can lead to variations in heart rate.
13:58 Tue 30th Apr 2002

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