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Adverse reaction on medication

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WendyS | 10:30 Tue 28th Mar 2006 | Body & Soul
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I believe there are some medications which should not be taken in conjunction with either grapefruit or fresh pineapple (not sure which) because of the adverse reaction from fruit enzymes. Can anybody enlighten me please?
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When I get simvastatin (cholesterol-lowering) from one chemist, there is a little sticker on the box advising me not to take grapefruit while on this medication, but the other chemist in town do not advise this.


I have never bothered to check this, because I don't eat many grapefruit , but I shall do a bit of research now out of interest.

Hi Wendy - it's grapefruit (& some oranges) that's the problem. Apparently it alters the way the body breaks down the medication & can result in too much of the drug being in the bloodstream.


there's a link here


I was on some medication for acne which had a link... Minocin I think it was.
Cranberry can also affect certain produts too.
Antidepressants. The SSRI's such as Seroxat,Cipralex,Sertraline and Efexor which is an SNRI.
Some medication for High Blood Pressure becomes too concentrated if you eat grapefruit.

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