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Guardian Cryptic 25,448

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maurice | 06:02 Sat 08th Oct 2011 | Crosswords
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21d: Upper chamber ll zonked out,rather pitifully,all starting to rise P?O?A?
and explanation please!
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prozac (upper) = initial letters of 'chamber all zonked out rather pitifully' reversed
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Many thanks,Bulliver:so simple when you see it!

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Guardian Cryptic 25,448

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