Yes, as long as you don't mind being limited to automatic cars.
I've got a 30+ year old car where you have to slam the gears around and it has to be driven and I love it, but also used to drive my flatmate's nan's Toyota Yaris (automatic) for little journeys round London and it's very easy, particularly if you have a lot of start/stop. Also used to drive her Dad's big automatic Lexus and that was very easy, although you can feel like it's driving you, but it is a bit like driving a big dodgem.
New manual cars are fairly easy to drive too, assuming you can manage a clutch and don't have any joint problems.