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Ninesome Reels?

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cinnabar | 19:12 Sun 25th Jan 2015 | Crosswords
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Just the thing for Burns Night?
Early maturing rodent, one spreading endless disease (9)
I know there is an E at position 5, otherwise the only letters I am sure of are R and A - there may also be a P, a T and another E. The layout of the puzzle - an extension of Azed's eightsome reels - I can't be sure where the beginning or end of the word is, so I don't know where the letters fit.
Any suggestions will be gratefully received - the rodent is presumably a rat, but I can't think what the disease might be . . .

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rheumatism?
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Thanks for the suggestion, but it has to have an E at position 5 - and I can't parse 'rheumatism' as the solution. I suspect the answer is a word that means 'early maturing' but I can't think of one other than 'precocious', and that doesn't fit anyway!
RAT + I 'spreading' HERPE(s) = RATHERIPE (ripening early)

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