Aircraft can and do , take off cruise to the destination and land totally automatically. There still have to be 2 human pilots but they are virtually redundant 95% of the time. There are driver-less trains on the DLR ( and many other places) and they are far safer than the trains with drivers. There are advanced studies to replace drivers with computer control on the London Underground, the only reason the drivers still have jobs is union resistance to the 1,000s of redundancies that will result. Ships again are normally on 'auto control' once out of the busiest shipping lanes.
Cambridge has buses that are self guided on the guided bus lanes, it was quite worrying the first time I was on one, the driver just folds his / her arms , sits back and lets the bus steer itself .