Not direct experience I'm afraid but the nurse I work with becomes evil if she doesn't take her HRT stuff apparently, (I've never noticed but then compared to me she's a fecking carebear ;o) She was having hot flushes, night sweats, no idea bout libido or weight gain, she's a very thin lady naturally so would doubt the latter. She says she feels much better with her HRT and obviosuly notices when she doesn't take it... as does her hubby apparently!