Last Three

[pnin]

Smoke half of joint, then kip (4) R-E-
More than one sure pharmacy's closing: a couple of tablets needed (5) Y-S-S
Local not for an alcoholic drink (4) -G-N (agin? but why?)

[elliemay1]

reek

[Lie-in King]

Guardian 28,117

3d Reek - 'ree(fer)' (half of joint) + 'k' (kip; Laos currency)
22d Yeses - '(pharmac)y' (closing) + 'E(cstasy tablets)'
23d Yes - Agin (local; dialect for "against") - 'a gin'

[aelmpvw]

agin local dialect for against