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manchesterun | 19:58 Tue 07th Jan 2020 | Crosswords
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64a put anend to pustule pimple or indeed acne , in epidermis by using a lot of wool
sr - i -
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Skein, a lot of wool. Skin, epidermis + there's an E at the end of pustule, pimple and acne.
Skein E in skin
SR?I?- is that the pattern?

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