I am on Symbicort for severe asthma and when a generic version was brought out most people in my area were changed onto it. My doctor wouldn't change me, but when I went to the local hospital for my regular checkup, the Registrar I saw said, she had been changed onto the ground generic version and it had affected her condition adversely. So, my advice is, if you think the Truxima is causing you problems, go and talk to your doctor and ask to be changed back to Retuximab.