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Has The Oxford Vaccine Be Hyped?

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Sunk | 18:46 Thu 26th Nov 2020 | News
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Astra/Zeneca’s share price has plummeted on fears that the vaccine will not be licensed for use in the USA.

Investors are doubting the results.
AZ originally claimed 70% effectiveness. That was bumped up to 90% on the results from two doses. But that turns out to have been done by error. A more clinical test of Brazilians only gave a 62% result.
There was criticism that the trial did not test on any older people, anyone over 55 was excluded.

62% is still impressive, but a third less than the other two. Have we been slightly misled?

https://www.theguardian.com/world/2020/nov/26/scrutiny-grows-over-oxford-universityastrazeneca-vaccine

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It's entirely appropriate to scrutinise the results, although it's worth noting that *all* drug companies so far have only announced preliminary vaccine studies. It's more important to back a vaccine that works than a vaccine that's made here. Given the choice, I want to see the Astra/Zeneca one working, not least because it will be the cheapest, offered...
19:50 Thu 26th Nov 2020
have a day off.
"that was bumped up to 90% on the results from two doses. But that turns out to have been done by error. " - yes but it was serendipitous, they discovered that half a dose + a later full dose is better. Stop it with the anti British codswallop.
the US were always going to favour their own vaccine.
Possably, will after wait and see. Theres been mixed stories on this which is concerning- my understanding was it had been shown to be effective on older peopel but if your right about over 55s been excluded thats contradictary
"62% is still impressive, but a third less than the other two. Have we been slightly misled?" - did you read your own post? it's 90% even if it was discovered by an error in dosage. Many things have been discovered by accident. Even in lefty anti British land.
Penicillin
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// "You've taken two studies for which different doses were used and come up with a composite that doesn't represent either of the doses," he said of the figure. "I think many people are having trouble with that." //

- David Salisbury, an associate fellow of the global health programme at the Chatham House think tank.

The mistake which resulted in the much better results were a smaller sample (about a quarter), and the sample were younger people who respond to treatments much better than the elderly.

TTT
AstraZeneca is a merger of the old ICI and a Swedish company. Scientists worldwide are sceptical of how the results have been presented. That is not anti-British. We will just have to wait and see if the AZ vaccine is effective and a commercial success.

Here is the Daily Torygraph being anti-British
https://www.telegraph.co.uk/news/2020/11/26/manufacturing-error-clouds-oxfords-covid-19-vaccine-study-results/

More measured responses from the snug.

Messenger shot.
Sunk, please remember that in TTT's simplistic world, everything
good is British and everything foreign is rubbish....and you are anti-British if you think otherwise.
It's entirely appropriate to scrutinise the results, although it's worth noting that *all* drug companies so far have only announced preliminary vaccine studies.

It's more important to back a vaccine that works than a vaccine that's made here. Given the choice, I want to see the Astra/Zeneca one working, not least because it will be the cheapest, offered at cost rather than with an inflated profit margin, but more than anything else, I want the vaccine to be subject to the highest standards of scrutiny to ensure that it's genuinely effective and safe.
Its interesting to me that the thrust of the criticism seems to be about/come from the USA where, as I understand it, the costs of the American vaccines are much higher and will be sold with the intention of making a profit.....if I was Pfizer and intent on making a profit, I'd have my worries about being both priced out and also ran because of the storage requirements.....just sayin'
I'm surprised at all you lefty types falling for this. Of course the US don't want a vaccine that's a couple of quid a go. Their big pharma want to charge what they like.
I did notice that a lot of criticism came from the US, but that's not a reason to ignore the potential for genuine issues. It's a matter of good practice to ensure that the data is accurate and that the issues, if any, are understood. I hope it's resolved favourably.

"Falling for this", indeed...
19.43 I think at times TTT feels very inferior, perhaps he ought to take a day off now and then.
normally profits horrify the spoon fed lefty types, I'd have thought one produced and charged at a couple of quid would sit well with our pretend socialists. It seems that anti Britishness is more important.
I just read this article in the Financial Times.

https://www.ft.com/content/4583fbf8-b47c-4e78-8253-22efcfa4903a
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PF
Is the FT a lefty anti-British publication like the Daily Torygraph ?

Sorry about that Woof.
It came up on my Google news feed. When I went back for the link, it was no longer there...so I looked for it and linked to the first FT article I found.

Sunk...I have no idea. Besides this is not about anti Britishness. Whatever that is. It's about how research is conducted and reported. Or so I thought. I'm not a scientist. I just want to know that the vaccine is safe, and will do what it's supposed to do, for as much of the population as possible.
Probably useful as backup when more successful vaccines are in short supply. Probably popular at the right price. But who knows what will prove best in the field trials.

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